Publications of the Toxicology Group

Researchers at the Toxicology chair group publish regularly in scientific journals, professional journals, scientific and popular books and proceedings.

Our publications

Use of a bacterial mutagenicity assay as a rapid method for the detection of early stage of Maillard reaction in orange juices.

Ekasari, I. , Jongen, W.M.F. , Pilnik, W. (1986) Food Chemistry (1986), Volume: 21 - ISSN 0308-8146 - p. 125-131.
Glutathione and cysteine mediated cytotoxicity of allyl and benzyl isothiocyanate.

Bruggeman, I.M. , Temmink, J.H.M. , van Bladeren, P.J. (1986) Toxicology and Applied Pharmacology (1986), Volume: 83 - ISSN 0041-008X - p. 349-359.
Toxicity of ozone and nitrogen dioxide to alveolar macrophages: comparative study revealing differences in their mechanism of toxic action.

Rietjens, I.M.C.M. , Poelen, M.C.M. , Hempenius, R.A. , Gijbels, M.J.J. , Alink, G.M. (1986) Journal of Toxicology and Environmental Health. Part A (1986), Volume: 19 - ISSN 1528-7394 - p. 555-568.
The microsomal metabolism of hexachlorobenzene. Origin of the covalent binding to protein.

van Ommen, B. , Adang, A.E.P. , Brader, L. , Posthumus, M.A. , Muller, F. , van Bladeren, P.J. (1986) Biochemical Pharmacology (1986), Volume: 35 - ISSN 0006-2952 - p. 3233-3238.
The microsomal metabolism of Dentachlorophenol and its covalent binding to protein and DNA.

van Ommen, B. , Adang, A.E.P. , Muller, F. , van Bladeren, P.J. (1986) Chemico-Biological Interactions (1986), Volume: 60 - ISSN 0009-2797 - p. 1-11.
Contribution of wood stoves and fire places to mutagenic activities of airborne particulate matter inside homes.

van Houdt, J.J. , Daenen, C.M.J. , Boleij, J.S.M. , Alink, G.M. (1986) Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis (1986), Volume: 171 - ISSN 0027-5107 - p. 91-98.
Chemical modification and inactivation of rat liver microsomal cytochrome P450c by 2-bromo-4'-nitroacetophenone.

Parkinson, A. , Ryan, D.E. , Thomas, P.E. , Jerina, D.M. , Sayer, J.M. , van Bladeren, P.J. , Haniu, M. , Shively, J.E. , Levin, W. (1986) Journal of Biological Chemistry (1986), Volume: 261 - ISSN 0021-9258 - p. 11478-11486.
Absolute configuration of benzo(c)phenanthrene 5,6-oxide and other k-region derivatives.

Sayer, J.M. , van Bladeren, P.J. , Yeh, H.J.C. , Jerina, D.M. (1986) Journal of Organic Chemistry (1986), Volume: 51 - ISSN 0022-3263 - p. 452-456.
A comparison of the mutagenicity of soluble trivalent chromium compounds with that of potassium chromate

Langerwerf, J.S.A. , Bakkeren, H.A. , Jongen, W.M.F. (1985) Ecotoxicology and Environmental Safety (1985), Volume: 9 - ISSN 0147-6513 - p. 92-100.
Genotoxicity testing of cigarette-smoke condensate in the SCE and HGPRT assays with V79 Chinese hamster cells

Jongen, W.M.F. , Hakkert, B.C. , van der Hoeven, J.C.M. (1985) Food and Chemical Toxicology (1985), Volume: 23 - ISSN 0278-6915 - p. 603-607.

Publications of the Toxicology Group

Our publications

Use of a bacterial mutagenicity assay as a rapid method for the detection of early stage of Maillard reaction in orange juices.

Glutathione and cysteine mediated cytotoxicity of allyl and benzyl isothiocyanate.

Toxicity of ozone and nitrogen dioxide to alveolar macrophages: comparative study revealing differences in their mechanism of toxic action.

The microsomal metabolism of hexachlorobenzene. Origin of the covalent binding to protein.

The microsomal metabolism of Dentachlorophenol and its covalent binding to protein and DNA.

Contribution of wood stoves and fire places to mutagenic activities of airborne particulate matter inside homes.

Chemical modification and inactivation of rat liver microsomal cytochrome P450c by 2-bromo-4'-nitroacetophenone.

Absolute configuration of benzo(c)phenanthrene 5,6-oxide and other k-region derivatives.

A comparison of the mutagenicity of soluble trivalent chromium compounds with that of potassium chromate

Genotoxicity testing of cigarette-smoke condensate in the SCE and HGPRT assays with V79 Chinese hamster cells

New approach methodologies (NAMs) to understand and predict drug-induced effects on bile acid homeostasis and cholestasis

The potential adverse and beneficial effects of hydroxyanthraquinones in traditional Chinese medicine (TCM)

Application of new approach : Methodologies for risk assessment of foodborne neurotoxic contaminants

Occurrence and thyroid hormone disrupting effects of food-borne chlorinated paraffins

Worms in Wonderland? : Evaluating the environmental risks of antidepressants using the nematode Caenorhabditis elegans

Quantify internal exposure levels of chemicals and their metabolites in wildlife using physiology based kinetic modelling

Advancing the understanding of neurotoxicity and mitigation strategies for α-dicarbonyl precursors of advanced glycation end products through new approach methodologies

Defining the relative potency of pyrrolizidine alkaloid N-oxides by new approach methodologies

Use of new approach methodologies to study the developmental toxicity of polycyclic aromatic hydrocarbons

Unravelling the functional dynamics between the human gut microbiome and intestinal inflammatory responses