Publications of the Toxicology Group

Researchers at the Toxicology chair group publish regularly in scientific journals, professional journals, scientific and popular books and proceedings.

Our publications

Methyl linoleate ozonide: a substrate for rat glutathione S-transferases.

Vos, R.M.E. , Rietjens, I.M.C.M. , Alink, G.M. , van Bladeren, P.J. (1987) European Journal of Drug Metabolism and Pharmacokinetics (1987), Volume: 12 - ISSN 0378-7966 - p. 275-277.
Identification of a reactive intermediate of furazolidone formed by swine liver microsomes.

Vroomen, L.H.M. , Groten, J.P. , van Muiswinkel, K. , van Veldhuizen, A. , van Bladeren, P.J. (1987) Chemico-Biological Interactions (1987), Volume: 64 - ISSN 0009-2797 - p. 167-179.
A co-cultivation system consisting of primary chick embryo hepatocytes and V79 Chinese hamster cells as a model for metabolic cooperation studies.

Jongen, W.M.F. , Sijtsma, S.R. , Zwijsen, R.M.I. , Temmink, J.H.M. (1987) Carcinogenesis (1987), Volume: 8 - ISSN 0143-3334 - p. 767-772.
The cytotoxicity of mercapturic acid pathway sulfur conjugates derived from benzyl and allyl isothiocyanate.

Bruggeman, I.M. , Temmink, J.H.M. , van Bladeren, P.J. (1986) Human toxicology (1986), Volume: 5 - ISSN 0144-5952 - p. 139-139.
Are cultured neonatal rat heart cells a suitable model for predictory acute and chronic toxicity in vivo?

Dorgelo, F.O. , Biessen, E.M. , Alink, G.M. (1986) ATLA-Alternatives To Laboratory Animals (1986), Volume: 14 - ISSN 0261-1929 - p. 14-22.
Naturally occurring carcinogens and modulating factors in food of plant origin.

Jongen, W.M.F. , Dorgelo, F.O. (1986) Netherlands Journal of Agricultural Science (1986), Volume: 34 - ISSN 0028-2928 - p. 395-404.
Oxidative metabolism by chick embryo hepatocytes: Induction of P-450 and the metabolism of benzo(a)pyrene.

Topp, R.J. , van Bladeren, P.J. (1986) Archives of Toxicology (1986), Volume: 59 - ISSN 0340-5761 - p. 150-155.
Resolution and absolute configuration of k-region-trans-dihydrodiols from polycyclic aromatic hydrocarbons.

Balani, S.K. , van Bladeren, P.J. , Shirai, N. , Jerina, D.M. (1986) Journal of Organic Chemistry (1986), Volume: 51 - ISSN 0022-3263 - p. 1773-1778.
Cytomorphological changes in liver cells exposed to benzyl and allyl isothiocyanate and their glutathione and cysteine conjugates.

Temmink, J.H.M. , Bruggeman, I.M. , van Bladeren, P.J. (1986) Archives of Toxicology (1986), Volume: 59 - ISSN 0340-5761 - p. 103-110.
Inhibitory effects of the phorbolester TPA and cigarette-smoke condensate on the mutagenicity of benzo(a)pyrene in a co-cultivation system.

Jongen, W.M.F. , Hakkert, B.C. , van de Poll, M.L.M. (1986) Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis (1986), Volume: 159 - ISSN 0027-5107 - p. 133-138.

Publications of the Toxicology Group

Our publications

Methyl linoleate ozonide: a substrate for rat glutathione S-transferases.

Identification of a reactive intermediate of furazolidone formed by swine liver microsomes.

A co-cultivation system consisting of primary chick embryo hepatocytes and V79 Chinese hamster cells as a model for metabolic cooperation studies.

The cytotoxicity of mercapturic acid pathway sulfur conjugates derived from benzyl and allyl isothiocyanate.

Are cultured neonatal rat heart cells a suitable model for predictory acute and chronic toxicity in vivo?

Naturally occurring carcinogens and modulating factors in food of plant origin.

Oxidative metabolism by chick embryo hepatocytes: Induction of P-450 and the metabolism of benzo(a)pyrene.

Resolution and absolute configuration of k-region-trans-dihydrodiols from polycyclic aromatic hydrocarbons.

Cytomorphological changes in liver cells exposed to benzyl and allyl isothiocyanate and their glutathione and cysteine conjugates.

Inhibitory effects of the phorbolester TPA and cigarette-smoke condensate on the mutagenicity of benzo(a)pyrene in a co-cultivation system.

New approach methodologies (NAMs) to understand and predict drug-induced effects on bile acid homeostasis and cholestasis

The potential adverse and beneficial effects of hydroxyanthraquinones in traditional Chinese medicine (TCM)

Application of new approach : Methodologies for risk assessment of foodborne neurotoxic contaminants

Occurrence and thyroid hormone disrupting effects of food-borne chlorinated paraffins

Worms in Wonderland? : Evaluating the environmental risks of antidepressants using the nematode Caenorhabditis elegans

Quantify internal exposure levels of chemicals and their metabolites in wildlife using physiology based kinetic modelling

Advancing the understanding of neurotoxicity and mitigation strategies for α-dicarbonyl precursors of advanced glycation end products through new approach methodologies

Defining the relative potency of pyrrolizidine alkaloid N-oxides by new approach methodologies

Use of new approach methodologies to study the developmental toxicity of polycyclic aromatic hydrocarbons

Unravelling the functional dynamics between the human gut microbiome and intestinal inflammatory responses