Publications of the Toxicology Group

Researchers at the Toxicology chair group publish regularly in scientific journals, professional journals, scientific and popular books and proceedings.

Our publications

Differential induction of rat hepatic glutathione S-transferase isoenzymes by hexachlorobenzene and benzylisothiocyanate.

Vos, R.M.E. , Snoek, M.C. , van Berkel, W.J.H. , Muller, F. , van Bladeren, P.J. (1988) Biochemical Pharmacology (1988), Volume: 37 - ISSN 0006-2952 - p. 1077-1082.
Organ specific metabolic activation of five extracts of indoor and outdoor particulate matter.

van Houdt, J.J. , Coenen, P.W.H.G. , Alink, G.M. , Boley, J.S.M. , Koeman, J.H. (1988) Archives of Toxicology (1988), Volume: 61 - ISSN 0340-5761 - p. 213-217.
Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys.

van den Berg, K.J. , Zurcher, C. , Brouwer, A. (1988) Toxicology Letters (1988), Volume: 41 - ISSN 0378-4274 - p. 77-86.
Modulating effects of B-naphto-flavone on the induction of SCEs by model compounds with emphasis on benzo(a)pyrene.

Jongen, W.M.F. , Sandker, G.W. , Goertz, M.P.H. , Topp, R.J. , van Bladeren, P.J. (1988) Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis (1988), Volume: 202 - ISSN 0027-5107 - p. 155-161.
Reversible interaction of a reactive intermediate derived from furazolidone with glutathione and protein.

Vroomen, L.H.M. , Berghmans, M.C.J. , Groten, J.P. , Koeman, J.H. , van Bladeren, P.J. (1988) Toxicology and Applied Pharmacology (1988), Volume: 95 - ISSN 0041-008X - p. 53-60.
Formation of toxic metabolites from drugs and other xenobiotics by glutathione conjugation.

van Bladeren, P.J. (1988) Trends in Pharmacological Sciences (1988), Volume: 9 - ISSN 0165-6147 - p. 295-298.
Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-penta-chlorobutadienyl)glutathione and N-acetyl.

Mertens, J.J.W.M. , Weijnen, J.G.J. , van Doorn, W.J. , Spenkelink, A. , Temmink, J.H.M. , van Bladeren, P.J. (1988) Chemico-Biological Interactions (1988), Volume: 65 - ISSN 0009-2797 - p. 283-293.
Differential effects of raising and lowering intracellular glutathione levels on the cytotoxicity of allyl isothiocyanate, tert-butylhydroperoxide and chlorod.

Bruggeman, I.M. , Spenkelink, A. , Temmink, J.H.M. , van Bladeren, P.J. (1988) Toxicology in Vitro (1988), Volume: 2 - ISSN 0887-2333 - p. 31-35.
Toxicity of airborne particulate matter to rat alveolar macrophages: a comparative study of five extracts collected indoors and outdoors.

van Houdt, J.J. , Rietjens, I.M.C.M. (1988) Toxicology in Vitro (1988), Volume: 2 - ISSN 0887-2333 - p. 121-123.
Effect of retinol and cigarette-smoke condensate on dye-coupled intercellular communication between hamster tracheal epithelial cells.

Rutten, A.A.J.J.L. , Jongen, W.M.F. , de Haan, L.H.J. , Hendriksen, E.G.J. , Koeman, J.H. (1988) Carcinogenesis (1988), Volume: 9 - ISSN 0143-3334 - p. 315-320.

Publications of the Toxicology Group

Our publications

Differential induction of rat hepatic glutathione S-transferase isoenzymes by hexachlorobenzene and benzylisothiocyanate.

Organ specific metabolic activation of five extracts of indoor and outdoor particulate matter.

Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys.

Modulating effects of B-naphto-flavone on the induction of SCEs by model compounds with emphasis on benzo(a)pyrene.

Reversible interaction of a reactive intermediate derived from furazolidone with glutathione and protein.

Formation of toxic metabolites from drugs and other xenobiotics by glutathione conjugation.

Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-penta-chlorobutadienyl)glutathione and N-acetyl.

Differential effects of raising and lowering intracellular glutathione levels on the cytotoxicity of allyl isothiocyanate, tert-butylhydroperoxide and chlorod.

Toxicity of airborne particulate matter to rat alveolar macrophages: a comparative study of five extracts collected indoors and outdoors.

Effect of retinol and cigarette-smoke condensate on dye-coupled intercellular communication between hamster tracheal epithelial cells.

New approach methodologies (NAMs) to understand and predict drug-induced effects on bile acid homeostasis and cholestasis

The potential adverse and beneficial effects of hydroxyanthraquinones in traditional Chinese medicine (TCM)

Application of new approach : Methodologies for risk assessment of foodborne neurotoxic contaminants

Occurrence and thyroid hormone disrupting effects of food-borne chlorinated paraffins

Worms in Wonderland? : Evaluating the environmental risks of antidepressants using the nematode Caenorhabditis elegans

Quantify internal exposure levels of chemicals and their metabolites in wildlife using physiology based kinetic modelling

Advancing the understanding of neurotoxicity and mitigation strategies for α-dicarbonyl precursors of advanced glycation end products through new approach methodologies

Defining the relative potency of pyrrolizidine alkaloid N-oxides by new approach methodologies

Use of new approach methodologies to study the developmental toxicity of polycyclic aromatic hydrocarbons

Unravelling the functional dynamics between the human gut microbiome and intestinal inflammatory responses