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Camelid Single Domain Antibodies
Single domain antibody fragments (sdAbs) from camelids retain full antigen-binding capacity. These so-called VHHs or nanobodies offer advantages compared to conventional antibodies. They possess unique properties such as small size, excellent solubility, superior stability, quick clearance from blood and deep tissue penetration. These distinctive qualities make them useful tools in a diverse array of applications such as biosensing, affinity-capture, protein crystallization, molecular imaging, tools for diagnosis and therapeutics.