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Projects - prof.dr. D (Dolf) Weijers
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Proteomic analysis of growth signaling integration in Arabidopsis
Plants, as sessile organisms, integrate various internal and environmental signals, such as hormones, light, and temperature, through intracellular... -
Concentration is key: unravelling mechanisms regulating Auxin Response Factor stability
We strive for a more complete understanding of how the phytohormone auxin steers virtually all developmental processes that constitute plant life. We... -
Origin and molecular reconstruction of the auxin response system
Hormone signalling allows organisms to regulate their physiology. Each hormone triggers multiple and complex, context-dependent responses that evolved... -
Developing a plant-specific CRISPR-Cas enzyme
CRISPR-Cas mediated genome editing is a technology that has revolutionised the biological sciences. However, though CRISPR-Cas mediated genome editing... -
Dissecting the ‘molecular compass’ SOSEKI1 by proteomics
To form a multicellular organism, all the cells need to “know” what is up and down, left and right, to adjust their divisions. Defects in... -
Breaking the symmetry in the early plant embryo
Formation of an adult plant body starting from a single cell is not a trivial task. For tissues and organs to be assembled into a particular shape... -
Understanding vascular development in ferns
The aim of this project is to better understand plant development in an evolutionary context by focusing on the more primitive plant group ferns. Much... -
Elucidating phase separation of transcription factors
We aim to characterize the functions of intrinsic disorder and phase separation during transcriptional control by ARF proteins in plants. ARFs have 3... -
Evolutionary biochemistry of the auxin signaling pathway
A largely unexplored question in biology is how hormone response networks emerged during evolution. In this project, we target this fundamental... -
Multi-omics data integration
Aim of this project is to identify and understand the evolutionarily conserved processes that play a key role in rapid auxin responses using...