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Projects - dr. DC (Daan) Swarts

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  Evolution and diversification of Argonaute proteins

  Argonaute (Ago) proteins are present in both eukaryotes and prokaryotes. In eukaryotes like humans, Agos control gene expression after transcription...
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  Developing a plant-specific CRISPR-Cas enzyme

  CRISPR-Cas mediated genome editing is a technology that has revolutionised the biological sciences. However, though CRISPR-Cas mediated genome editing...
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  Characterization of unexplored prokaryotic Argonaute proteins

  Prokaryotic Argonautes are a large family of proteins that are, among other things, involved in immunity against invading nucleic acids. However, many...
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  Characterisation of novel prokaryotic Argonaute Systems

  Prokaryotes are under constant threat of invading nucleic acids such as viruses and plasmids. To withstand infection by these nucleic acids,...
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  Unraveling mechanisms of Prokaryotic Argonautes

  Prokaryotic Argonautes (pAgos) are a diverse group of proteins that can use DNA/RNA guides to target complementary DNA/RNA targets. They protect their...