Publications

Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p

Lu, D.; Liu, Yisi; Kang, Luyuan; Zhang, Xiangyu; Hu, Jie; Ye, H.; Huang, Bingxu; Wu, Yujun; Zhao, Jinbiao; Dai, Zhaolai; Wang, Junjun; Han, Dandan

Summary

The intestinal development in early life is profoundly influenced by multiple biological components of breast milk, in which milk-derived extracellular vesicles (mEVs) contain a large amount of vertically transmitted signal from the mother. However, little is known about how maternal fiber-rich diet regulates offspring intestinal development by influencing the mEVs.