Publications

Recombinant activation-associated secreted protein

Geldhof, Peter; Zwanenburg, Laurens; Borloo, Jimmy; Wilbers, Ruud; Hokke, Cornelis Hendrik; Van Diepen, Angela

Summary

The present invention relates to a recombinant activation-associated secreted protein (ASP) or fragment thereof, said ASP or fragment comprising an N-glycan comprising a core α1,3-fucose and/or a core α1,6-fucose (Fuc). The invention further relates to a pharmaceutical composition comprising such a recombinant ASP or fragment thereof. Additionally, the invention relates to the recombinant ASP or fragment thereof for use as a human or veterinary medicine, in particular as a vaccine, more in particular for use against parasitic nematode infections.