The SoFiT trial: Healthy lifestyle and fatigue after colorectal cancer

Colorectal cancer is among the top five most prevalent types of cancer in the Netherlands. Almost one in three colorectal cancer survivors suffer from fatigue, which has a major impact on quality of life. Previous research showed that patients who exercise more and eat healthier after colorectal cancer experience a better quality of life than those who do not.

Fatigue after colorectal cancer

The SoFiT trial aimed to determine whether there is a causal link between a healthier lifestyle and fatigue. A multidisciplinary team of nutrition scientists, behavioural scientists, healthcare professionals and patients started the SoFiT trial in January 2022, and completed it in December 2024. Details on the design of the project can be read here: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/randomised-controlled-intervention-trial-to-study-the-effect-of-a-personalised-lifestyle-programme-on-cancerrelated-fatigue-among-colorectal-cancer-survivors-protocol-for-the-sofit-study/A55000756A6588A3B35CE37EEC841E79)