SDG (Sam) Oakley

I am currently pursuing a PhD centred on the intricate role that branched-chain amino acids (BCAAs) play in the regulation of skeletal muscle mass and their broader implications for metabolic health, particularly with respect to insulin sensitivity. My research investigates the mechanisms through which BCAAs influence muscle protein synthesis and how they may contribute to the changes in insulin sensitivity, offering potential therapeutic insights for conditions such as metabolic syndrome and type 2 diabetes.

My academic journey has consistently been driven by a passion for understanding the factors that influence muscle mass gain and loss. During my undergraduate studies, I explored the role of omega-3 fatty acids in promoting recovery from exercise-induced muscle damage. This work sparked my interest in how nutrition can be harnessed to enhance muscle repair and regeneration. Building on this foundation, my MSc research delved into the effects of omega-3 supplementation on strength gains and hypertrophy adaptations, furthering my understanding of how dietary interventions may optimise muscle function and growth.

With a keen interest in the intersection of nutrition, metabolism, and muscle health, my current work aims to advance our understanding of how BCAAs contribute to both skeletal muscle anabolism and the regulation of metabolic pathways. Ultimately, my goal is to develop interventions that can support healthy muscle ageing, improve metabolic outcomes, and enhance performance in both athletic and clinical populations.

Outside of my core research, I am deeply invested in the broader field of muscle physiology and am continually exploring new methodologies and approaches to studying muscle mass dynamics. My work is part of a larger effort to address key challenges in public health related to muscle loss and metabolic dysfunction.