PhD defence

On obliterating the initial barriers of polyploidy: insights from Nasonia neopolyploids

PhD candidate S (Saminathan) Sivaprakasham Murugesan MSc
Promotor prof.dr. M (Marcel) Dicke
External promotor Prof. Dr Leo W. Beukeboom
Co-promotor dr. EC (Eveline) Verhulst
Organisation Wageningen University, Laboratory of Entomology
Date

Fri 14 March 2025 13:00 to 14:30

Venue Omnia, building number 105
Hoge Steeg 2
105
6708 PH Wageningen
+31 (0) 317 - 484500
Room Auditorium

Summary

This research explores how having extra sets of chromosomes (polyploidy) affects the development and gene activity of the parasitic wasp Nasonia vitripennis. While polyploidy is common in plants, it is rare in animals. By studying both a long-established polyploid wasp line and newly created polyploid lines, this work examines how they cope with extra genetic material. The findings show that polyploid wasps adjust their cell size, gene expression, and biological processes over generations. Early-generation polyploids experience genetic instability, while long-term polyploids develop mechanisms to manage their larger genomes. This research provides insights into how animals adapt to genome duplication, with implications for evolution, genetics, and even pest control applications.