PhD defence

Drive safely – An exploration of Super-Mendelian inheritance by CRISPR-Cas based gene drives

PhD candidate AC (Carina) Nieuwenweg PhD
Promotor prof.dr. J (John) van der Oost
Co-promotor dr. RHJ (Raymond) Staals
Organisation Wageningen University, Laboratory of Microbiology
Date

Fri 28 June 2024 13:30 to 15:00

Venue Omnia, building number 105
Hoge Steeg 2
105
6708 PH Wageningen
+31 (0) 317 - 484500
Room Auditorium

Summary

While CRISPR-Cas has revolutionized genome editing by enabling precise DNA alterations, CRISPR-Cas-based gene drive technology allows these genetic changes to rapidly spread through entire populations. Typically used for pest control, in this thesis gene drive technology is exploited to modify DNA in baker's yeast, demonstrating effective genetic changes across generation