PhD defence

Bifidobacterium breve & Streptococcus thermophilus: Novel aspects of these beneficial bacteria

Promotor prof.dr. EJ (Eddy) Smid
Co-promotor prof.dr. T (Tjakko) Abee
dr. O (Oscar) van Mastrigt
Organisation Wageningen University
Date

Thu 20 March 2025 10:30 until Wed 20 March 2024 11:30

Venue Omnia, building number 105
Hoge Steeg 2
105
6708 PH Wageningen
+31 (0) 317 - 484500
Room Auditorium

Summary

Bifidobacterium breve and Streptococcus thermophilus are two beneficial bacteria that have been widely studied and used in fermented food products for human consumption. B. breve has been primarily used as probiotic bacteria and S. thermophilus as starter bacterial culture in the elaboration of dairy products.
These bacteria are currently used together in the production of infant formula which has proven to have beneficial effects in infants, which include the stimulation of the immune system, positive modulation of the gut microbiota and reduction of acute diarrhea. However, some aspects that explain how these bacteria function under certain conditions are unknown. In this thesis, several aspects of these two probiotic bacteria were investigated individually and in co-culture to look further in depth some of the mechanisms with which they produce positive effects on the host.